High Quality Pharmaceutical Raw Materials Nitrofurazone Powder CAS 59-87-0

Basic Info

Model NO.	59-87-0
Storage Condition	Store at Rt
Transport Package	Aluminium Foil Bag
Specification	kg
Trademark	FOUSI
Origin	China
HS Code	2932190090
Production Capacity	100000kg/Month

Product Description

High Quality Pharmaceutical Raw Materials Nitrofurazone Powder CAS 59-87-0

High Quality Pharmaceutical Raw Materials Nitrofurazone PowderCAS 59-87-0

Product Description

Product Name:Nitrofurazone

CAS NO.: 59-87-0

EINECS NO.: 200-443-1

Mol Fm:C6H6N4O4

Mol Wt: 198.14

Appearance : yellow crystal power

Nitrofurazone is a topical anti-infective and bactericide for most pathogens commonly causing surface infections; in the adjunctive therapy of patients with second and third degree bums when bacterial resistance to other agents is areal or potential problem; in skin grafting where bacterial contamination may cause graft rejection and/or donor-site infection; antibacterial agent for the treatment or prevention of infections in a variety of conditions involving skin, eyes, ears, nose and genito-urinary tract; used on pyodermas, ulcers, and wounds; affects some protozoa and is an effective prophylaxis against nosocomial infections; antiseptic lubricant for trans urethral resection; anti-microbial in veterinary medicine.

Product picture

Product Parameters

Items of Test	Limits of Test	Result of Test
Appearance	A yellow or brownish-yellow, crystalline powder	Conforms
Identification A,B,C,D	Conforms	Conforms
Ph	5.0-7.0	6.7
Loss on Drying	≤0.5%	0.29%
Heavy Metals	≤0.002%	less than0.002%
Sulphate ash	≤0.1%	0.08%
Individual impurity	≤0.5%	less than0.5%
Total impurities	≤1.0%	less than1.0%
Assay	97.0%-103%	99.85%

Application

Nitrofural is a bactericidal compound used as an antibiotic most commonly in the form of ointments.Target: AntibacterialNitrofurazone, a nitroaromatic drug, is a broad spectrum antibiotic which has until now been considered as activated in bacteria by nitroreductases. Its use in medicine has become less frequent as safer and more effective products have become available, and it has been discontinued in the US.Nitrofurazone (NF) and its derivative, hydroxymethylnitrofurazone (NFOH), have presented antichagasic activity. In vitro cruzain inhibition tests were performed for both compounds, and the 50% inhibitory concentration (IC50) for NF and NFOH presented values of 22.83 ± 1.2 μM and 10.55 ± 0.81 μM, respectively. AM1 semi-empirical molecular modeling studies were performed to understand the activity of the compounds, corroborating the observed cruzain inhibitory activity.

1. This product is a nitrofuran antibacterial. These drugs also include furazolidone and nitrofurantoin. Nitrofurazone is orally toxic and is used for surgical topical or surface disinfection.
2. Nitrofuran antibacterials, mainly used for disease prevention and antibacterial of poultry, livestock and aquatic fish.
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High Quality Pharmaceutical Raw Materials Nitrofurazone Powder CAS 59-87-0